When is Sperm DNA fragmentation (SDF) testing recommended?
SDF testing is recommended for men with varicoceles (enlarged veins within the scrotum) idiopathic or unexplained infertility recurrent pregnancy loss recurrent IVF treatment failure abnormal semen parameters resulting from defective sperm maturation and premature cell death exposure to modifiable lifestyle risk factors, including heat exposure, smoking, environmental pollutants, and chemotherapeutics.