Micro-TESE is conducted in the male patient under general anesthesia. A cut is made in the testis to search for the tubules containing sperms. Each testicle is examined under a high-power operating microscope. The surgeon searches for seminiferous tubules especially the swollen tubules which contain sperm. Later the testis is closed with very fine dissolvable sutures. The patient can go home after the procedure and should be able to do normal activities within 1 to 2 weeks.
If sperms are found during the procedure, they are extracted and used immediately to fertilize an egg or the sperm cells can be frozen, stored for future reproductive treatment using ICSI.