Endometrial Receptivity Analysis (ERA)

Endometrial Receptivity Analysis (ERA)

Endometrial Receptivity Analysis (ERA) is a test to assess the endometrial status and determine the presence of a receptive gene profile in the patient’s endometrium during the biopsy.

The human endometrium is a highly dynamic tissue that is capable of undergoing physiological changes in response to steroid hormones. Thus, it creates a receptive status that is synchronized with the arrival of an implanting blastocyst (refers to an embryo that is 5 days old after successful fertilization).

Who should consider ERA?

The ERA is considered in women who:

  • Experienced multiple implantation failures with embryo transfers despite good quality of the embryos
  • No previous pregnancies

Also Read: Frozen Embryo Transfer Procedure: All You Want to Know

What is Endometrial Receptivity Genome Analysis?

Endometrial Receptivity Genome Analysis is a state-of-the-art diagnostic method. This test evaluates the endometrial receptivity status from a molecular point of view. It helps to assess the receptivity for endometrium for implantation by analyzing the expression of a group of genes related to endometrial receptivity.

Frequently Asked Questions

  1. What is the ERA test in IVF?

    The ERA test, or Endometrial Receptivity Analysis, checks whether the lining of the uterus is ready for embryo implantation. It analyzes gene activity in a small endometrial biopsy to determine the optimal timing for embryo transfer, thereby improving the chances of pregnancy in IVF.

  2. How to check endometrial receptivity?

    Endometrial receptivity is checked through the ERA test. A small sample of the uterine lining is taken during a mock cycle and analyzed for specific genes. The results indicate whether the endometrium is receptive or whether the embryo transfer timing needs adjustment.

  3. How much does ERA testing cost in IVF?

    ERA testing helps optimize IVF success by identifying the best time for embryo transfer. At ART Fertility Clinics, the procedure costs 4,650 AED, which includes the biopsy and genetic analysis. This test provides valuable data to personalize your treatment plan, particularly if you have experienced previous implantation challenges.

  4. Why is the ERA test done?

    The ERA test is done to identify the best window for embryo implantation. It is mainly recommended for women who have had multiple failed embryo transfers despite good-quality embryos, helping personalize embryo transfer timing and increase the chance of a successful pregnancy.

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