Dr. Laura Melado Vidales

Specialist Reproductive Medicine and Infertility

Medical Director, ART Fertility Clinics, Abu Dhabi

Dr. Melado is Specialist in Obstetrics, Gynaecology and Reproductive Endocrinology/IVF for Health Authority Abu Dhabi (HAAD) and Dubai Health Authority (DHA). She completed her bachelor’s degree in Medicine and Surgery (University Autónoma in Madrid) in 2002, and her fellowship in Obstetrics and Gynaecology for 4 years at the Hospital Universitario La Paz, Madrid (2003-2007), with a rating of Excellent. She completed her Habilitation Thesis on ¨AMH during controlled ovarian stimulation: variability and correlation with IVF outcomes¨ in 2015 with Cum Laude (University Autónoma in Madrid).

As a doctor, she has worked as Ob/Gyn and IVF and Fertility Consultant in Madrid, Spain. After moving to UAE, she joined IVIRMA Middle East in 2016, collaborating in Abu Dhabi and Dubai Clinic.

Dr. Laura Melado is an author of more than 25 internationally peer-reviewed articles and book chapters. Her main research is focused on ovarian reserve and anti-Müllerian hormone (AMH), one of the most important markers for ovarian reserve.

She has participated as a speaker in several international conferences and is also a member of European Society of Human Reproduction and Embryology (ESHRE), Spanish Board of Obstetrics and Gynaecology (SEGO) and Spanish Fertility Society (SEF).

English and Spanish

Abu Dhabi

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Experience

Fellowship in Obstetrics and Gynecology for 4 years at the Hospital Universitario La Paz, Madrid (years 2003-2007), with a rating of Excellent.
Specialist OB/BYN, Hospital La Paz since June 2007, incorporating the Service for Fertility and Assisted Reproduction (Dr. Carmen Cuadrado), since May 2008.
Specialist in Cervical Pathology and Colposcopy (Dr Calvo de Mora Clinic, period January 2007-January 2008).
Specialist OB/GYN and Infertility, Hospital Quiron Madrid, from January 2009 until July 2011.
Consultant IVF and Fertility Endocrinologist OB/GYN, Clinica Ginefiv (from July 2011 to October 2015).
Specialist Obstetrics and Gynecology and Reproductive Endocrinology IVF in Al Ain Fertility Center (AAFC) from October 2015 to August 2016 (Al Ain, Abu Dhabi, UAE).
Specialist Obstetrics and Gynecology and Reproductive Endocrinology IVF in ART Fertility Clinics (Abu Dhabi and Dubai).

Educational Qualification

Consultant Obstetrics, Gynecology and Infertility, Colegio Oficial de Médícos de Madrid (Spain)
Specialist Obstetrics and Gynecology and Reproductive Endocrinogy IVF for Health Authority Abu Dhabi (HAAD) and Dubai Health Autorithy (DHA)
Member of European Society of Human Reproduction and Embryology (ESHRE), Spanish Board of Obstetrics and Gynecology, Spanish Fertility Society (SEF), Spanish Society of Obstetrics and Gynecology (SEGO)
PhD, Universidad Autonoma de Madrid: “Antinüllerian hormone dynamics during IVF treatment and correlation with pregnancy rates”. Readed March 23th 2015, with a distinction “cum laude” given unanimously
Bachelor of Medicine and Surgery from the Autonoma University of Madrid (1996-2002). Fellowship in Gynecology and Obstetrics at the Hospital Universitario La Paz (Madrid) 2003-2007.

Publications

Segmental duplications and monosomies are linked to in vitro developmental arrest. De Munck, N; Bayram, A; Elkhatib, I; Liñán, A; Arnanz, A; Melado, L; Lawrenz, B; Fatemi M, H. Journal of Assisted Reproduction and Genetics, No. JARG-D-20-01128R2. Accepted for publication on March 9th, 2021.
Vitamin D in Follicular Fluid Correlates With the Euploid Status of Blastocysts in a Vitamin D Deficient Population. Arnanz A, De Munck N, El Khatib I, Bayram A, Abdala A, Melado L, Lawrenz B, Coughlan C, Pacheco A, Garcia-Velasco JA and Fatemi HM (2021). Front. Endocrinol. 11:609524. doi: 10.3389/fendo.2020.609524
Inhibin A-A Promising Predictive Parameter for Determination of Final Oocyte Maturation in Ovarian Stimulation for IVF/ICSI. Lawrenz B, Depret Bixio L, Coughlan C, Andersen CY, Melado L, Kalra B, Savjani G, Fatemi HM, Kumar A. Front Endocrinol (Lausanne). 2020 May 15;11:307. doi: 10.3389/fendo.2020.00307. PMID: 32499758; PMCID: PMC7243678.
Anti-müllerian hormone is an independent marker for oocyte survival post-vitrification. L. Melado, A. Arnanz, A. Bayram, I. Elkhatib, N. De Munck, A.T. Navarro, C. Coughlan, B. Lawrenz, H.M. Fatemi. Reprod Biomed Online 2020 Jul;41(1):119-127. doi: 10.1016/j.rbmo.2020.03.014.Epub 2020 Apr 28.
Blastocyst mitochondrial DNA (mtDNA) is not affected by oocyte vitrification: a sibling oocyte study. Arnanz, A., De Munck, N., Bayram, A. El-Damen, A., Abdalla, A., ElKhatib, I., Melado, L., Lawrenz, B., Fatemi, HM. J Assist Reprod Genet 2020 Jun;37(6):1387-1397. doi: 10.1007/s10815-020-01795-6.Epub 2020 May 6.
The ART of frozen embryo transfer: back to nature! Lawrenz B, Coughlan C, Melado L, Fatemi HM. Gynecol Endocrinol 2020 Jun;36(6):479-483. doi: 10.1080/09513590.2020.1740918.Epub 2020 Mar 18.PMID:32188299
Intracytoplasmic sperm injection is not superior to conventional IVF in couples with non-male factor infertility and preimplantation genetic testing for aneuploidies (PGT-A). De Munck N, El Khatib I, Abdala A, El-Damen A, Bayram A, Arnanz A, Melado L, Lawrenz B, Fatemi HM.
Hum Reprod. 2020 Feb 29;35(2):317-327. doi: 10.1093/humrep/deaa002. PMID:32086522
Isthmocele and ovarian stimulation for IVF: considerations for a reproductive medicine specialist. Lawrenz B, Melado L, Garrido N, Coughlan C, Markova D, Fatemi H.
Hum Reprod. 2020 Jan 1;35(1):89-99. doi: 10.1093/humrep/dez241.PMID: 31885047
Inter-assay variation and reproducibility of progesterone measurements during ovarian stimulation for IVF.
Lawrenz B, Sibal J, Garrido N, Abu E, Jean A, Melado L, Fatemi HM.
PLoS One. 2018 Nov 1;13(11):e0206098. doi: 10.1371/journal.pone.0206098. eCollection 2018. PMID:30383804
Ethnical and sociocultural differences causing infertility are poorly understood-insights from the Arabian perspective.
Lawrenz B, Coughlan C, Melado L, Fatemi HM.
J Assist Reprod Genet. 2019 Apr;36(4):661-665. doi: 10.1007/s10815-019-01411-2. Epub 2019 Jan 26. PMID: 30685837
Anti-müllerian Hormone During Natural Cycle Presents Significant Intra and Intercycle Variations When Measured With Fully Automated Assay.
Melado L, Lawrenz B, Sibal J, Abu E, Coughlan C, Navarro AT, Fatemi HM.
Front Endocrinol (Lausanne). 2018 Nov 27;9:686. doi: 10.3389/fendo.2018.00686. eCollection 2018. PMID:30542322
Inter-assay variation and reproducibility of progesterone measurements during ovarian stimulation for IVF.
Lawrenz B, Sibal J, Garrido N, Abu E, Jean A, Melado L, Fatemi HM.
PLoS One. 2018 Nov 1;13(11):e0206098. doi: 10.1371/journal.pone.0206098. eCollection 2018.
Fully automated assay assessment of intra- and inter-cycle variation for Anti-Müllerian hormone during the natural cycle. Melado, L; Lawrenz, B; Sibal, J; Abu, E; Navarro, A; Fatemi, HM. Poster presentation during the 34th Annual Meeting of the European Society of Human Reproduction and Embryology, held at Centre de Convencions Internacional de Barcelona (CCIB) in Barcelona, Spain from 1 to 4 July 2018.
Anti-Müllerian hormone variability during ovarian stimulation for IVF: A novel approach to predict fertility treatment outcomes. Mini review. Laura Melado MD, Barbara Lawrenz MD, Leif Bungum MD, Human Fatemi MD. J Reprod Biol Endocrinol. 2018;2(1):33-34.
Luteal Coasting and Individualization of Human Chorionic Gonadotropin Dose after Gonadotropin-Releasing Hormone Agonist Triggering for Final Oocyte Maturation-A Retrospective Proof-of-Concept Study. Lawrenz B, Samir S, Garrido N, Melado L, Engelmann N, Fatemi HM. Front Endocrinol (Lausanne). 2018 Feb 15;9:33. doi: 10.3389/fendo.2018.00033. eCollection 2018.
Premature progesterone rise in ART-cycles. Lawrenz B, Melado L, Fatemi HM. Reprod Biol. 2018 Jan 6. pii: S1642-431X(17)30299-1.
doi:10.1016/j.repbio.2018.01.001.
Luteal phase serum progesterone levels after GnRH-agonist trigger – how low is still high enough for an ongoing pregnancy? Lawrenz B, Samir S, Melado L, Ruiz F, Fatemi HM. Gynecol Endocrinol. 2017 Oct 16:1-4. doi: 10.1080/09513590.2017.1391204.
Individual luteolysis pattern after GnRH- agonist trigger for final oocyte maturation. Barbara Lawrenz, Nicolas Garrido, Suzan Samir, Francisco Ruiz, Laura Melado, Human M. Fatemi. PLOS ONE | https://doi.org/10.1371/journal.pone.0176600 May 1, 2017.
Anti-Müllerian hormone levels to predict oocyte maturity and embryo quality during controlled ovarianhyperstimulation. Melado Vidales L, Fernández-Nistal A, Martínez Fernández V, Verdú Merino V, Bruna Catalán I, Bajo Arenas JM. Minerva Ginecol. 2017 Jun;69(3):225-232. doi: 10.23736/S0026-4784.16.03958-7. Epub 2016 Jun 28. PMID: 27352270
Anti-Müllerian hormone dynamics during GNRH-antagonist short protocol for IVF/ICSI in women with varying ovarian reserve levels. Melado Vidales L, Fernández-Nistal A, Martínez Fernández V, Verdú Merino V, Bruna Catalán I, Bajo Arenas JM. Minerva Ginecol. 2017 Apr;69(2):128-134. doi: 10.23736/S0026-4784.16.03951-4. Epub 2016 Jun 16. PMID: 27310675
Modified Vecchietti’s vaginoplasty with Remeex system in patient with chronic graft-versus-host disease. Melado Vidales, Laura; Muñoz Muñiz, Mar; Santisteban Padro, Javier. Open Journal of Obstetrics and Gynecology, 2012, 2, 85-88.
Hormone therapy as first treatment in patients with operable breast cancer.L. Melado Vidales, G. Hernandez Cortes, M. Muñoz Muñiz, J. Santiago Garcia, J. Ordás Santo Tomas. Prog Obstet Gynecol 2009; 52 (1) :11-21.
Comparison of the intrauterine system releasing levonorgestrel (Mirena) and endometrial ablation in the treatment of dysfunctional uterine bleeding. Laura Melado V, Monica Novelle G, Alicia Hernandez G, Mar Muñoz M, Juan Ordas ST. Rev Chil Obstet Gynecol 2008; 73 (4): 263-267.
Melado Vidales L, Herrero Ruiz B, Rodriguez Gonzalez R, Alvarez Charines E, Herrero de Lucas L, Gonzalez Gonzalez A. Abdominal situs inversus and azygos-IVC continuity. Case report. Prog Obstet Gynecol 2008; 51 (6) :355-9.
Melado Vidales L, Hernandez Gutierrez A, Munoz Muniz MM, Thomas J. Ordás Deep infiltrating endometriosis, case report. Prog Obstet Gynecol 2007; 50 (10) :609-14.
Melado Vidales L, Sánchez Hernández MJ, Martos MA Cano, Molina MM Hita, M. Naranjo Sancha. Fatal anaphylactic shock during the course of a cesarean section. Prog Obstet Gynecol 2005, 48 Suppl 2:343-345.
Chapters in books:
Laura Melado and Human M. Fatemi. Chapter 1: Individualized Ovarian Stimulation for Normal and High Responders. BOOK: Individualized In Vitro Fertilization: Delivering Precision Fertility Treatment. Edited by Human M. Fatemi & Barbara Lawrenz.Cambridge, United Kingdom ; New York, NY : Cambridge University Press, 2021. | Identifiers: LCCN 2020029466 (print) | LCCN 2020029467 (ebook) | ISBN 9781108799683 (paperback) |ISBN 9781108891622 (ebook) Subjects: MESH: Fertilization in Vitro – methods | Precision Medicine – methods | Infertility – therapy Classification: LCC RG135 (print) | LCC RG135 (ebook) | NLM WQ 208 | DDC 618.1/780599–dc23LC record available at https://lccn.loc.gov/2020029466LC ebook record available at https://lccn.loc.gov/2020029467 ISBN 978-1-108-79968-3 Paperback
Laura Melado, Barbara Lawrenz, and Human Fatemi. Use of Luteal Phase Support. BOOK: Controversies in Assisted Reproduction. CRC Press, Taylor & Francis Group. 2020.
Laura Melado Vidales, MD, PhD, y Diana Alecsandru, MD, PhD. CONCEPTOS BÁSICOS DE INMUNOBIOLOGÍA DE LA REPRODUCCIÓN HUMANA. Actualización texto de Obstetricia, Universidad El Bosque, Bogotá, Colombia.
Dr. Laura Melado Vidales and Dr Ginés Hernandez Cortes. Homone Therapy: the only Treatment in Patients with hormone-elderly breast carcinoma sentitive unsuitable to surgical Treatment. Chapter 3. In: Cancer in the elderly. Nova Science Publishers, Inc. © 2011.
Aspects sonographic endometrial preparation for frozen embryo transfer. Authors: V.G.Villafáñez, V.Verdú, V. Lucas, L. Melado, J.M. Under Arenas. In press.
The antral follicle count as a determinant of follicular reserve. Dr V. Verdú, Dr V G.Villafañez, Dr V Lucas, Dr L Melado, Prof BajoArenas.